AP3D1 rabbit pAb
Ucallm_WP7266-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | AP3D1 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 127kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human AP3D1 |
| Specificity | This antibody detects endogenous levels of AP3D1 at Human, Mouse |
| Gene Name | AP3D1 PRO0039 |
| Protein Name | AP-3 complex subunit delta-1 (AP-3 complex subunit delta) (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin) |
| Other Name | |
| Species | Human |
| Gene ID | 8943 |
| Uniprot | O14617, |
| Species.1 | Mouse |
| Gene ID.1 | 11776 |
| Uniprot.1 | O54774 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side . |
| Tissue Expression | Present in all adult tissues examined with the highest levels in skeletal muscle, heart, pancreas and testis. |
| Signaling_pathway | Cellular Processes >> Transport and catabolism >> Lysosome |
| Research Areas | |
| Function | Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Involved in process of CD8+ T-cell and NK cell degranulation . In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals (By similarity). |
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