Product details
Background:
AP5Z1/SPG48 rabbit pAb
Ucallm_WP8964-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | AP5Z1 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 89kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human AP5Z1/SPG48 |
| Specificity | This antibody detects endogenous levels of AP5Z1/SPG48 at Human, Mouse |
| Gene Name | AP5Z1 KIAA0415 SPG48 |
| Protein Name | AP-5 complex subunit zeta-1 (Adapter-related protein complex 5 zeta subunit) (Zeta5) |
| Other Name | |
| Species | Human |
| Gene ID | 9907 |
| Uniprot | O43299, |
| Species.1 | Mouse |
| Gene ID.1 | 231855 |
| Uniprot.1 | Q3U829 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Nucleus . By SDS-PAGE, 2 isoforms have been observed, the shorter seems to be predominantly nuclear and the longer is mostly cytoplasmic. . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed:20613862 it is a putative helicase required for efficient homologous recombination DNA double-strand break repair. |
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