Price range: $268.00 through $328.00
Background:
The protein encoded by this gene is an aquaporin protein, which functions as a water channel in cells. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This protein is specific for the kidney. This gene and related family members AQP0, AQP2, and AQP5 reside in a cluster on chromosome 12q13. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | AQP6 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 31kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 60-140 |
| Specificity | AQP6 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | AQP6 AQP2L |
| Protein Name | Aquaporin-6 (AQP-6) (Aquaporin-2-like) (Kidney-specific aquaporin) (hKID) |
| Other Name | |
| Species | Human |
| Gene ID | 363 |
| Uniprot | Q13520, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q8C4A0, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q9WTY0 |
| Cellular Localization | Cytoplasmic vesicle membrane; Multi-pass membrane protein . |
| Tissue Expression | Kidney,Testis, |
| Signaling_pathway | |
| Research Areas | |
| Function | Domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,Function:Forms a water-specific channel that participates in distinct physiological functions such as glomerular filtration, tubular endocytosis and acid-base metabolism.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family., |
