Price range: $268.00 through $328.00
Background:
Aquaporin 8 (AQP8) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 8 mRNA is found in pancreas and colon but not other tissues. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | AQP8 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 28kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 70-150 |
| Specificity | AQP8 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | AQP8 |
| Protein Name | Aquaporin-8 (AQP-8) |
| Other Name | |
| Species | Human |
| Gene ID | 343 |
| Uniprot | O94778, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P56404, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | P56405 |
| Cellular Localization | Mitochondrion membrane; Multi-pass membrane protein . |
| Tissue Expression | Detected in the sperm midpiece (at protein level) (PubMed:28042826). Expressed only in pancreas and colon. |
| Signaling_pathway | |
| Research Areas | >>Bile secretion |
| Function | Domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,Function:Forms a water-specific channel; mercury-sensitive. Not permeable to glycerol or urea.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family.,tissue specificity:Expressed only in pancreas and colon., |
