AQP9 Polyclonal Antibody
Ucallm_WP0882-50
Price range: $268.00 through $328.00
Product details
Background:
The aquaporins are a family of water-selective membrane channels. This gene encodes a member of a subset of aquaporins called the aquaglyceroporins. This protein allows passage of a broad range of noncharged solutes and also stimulates urea transport and osmotic water permeability. This protein may also facilitate the uptake of glycerol in hepatic tissue . The encoded protein may also play a role in specialized leukocyte functions such as immunological response and bactericidal activity. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
Specifications
| Size | 50μL/100μL |
| Target | AQP9 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 32kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 160-240 |
| Specificity | AQP9 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | AQP9 SSC1 |
| Protein Name | Aquaporin-9 (AQP-9) (Aquaglyceroporin-9) (Small solute channel 1) |
| Other Name | |
| Species | Human |
| Gene ID | 366 |
| Uniprot | O43315, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9JJJ3, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | P56627 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein . |
| Tissue Expression | Highly expressed in peripheral leukocytes. Also expressed in liver, lung, and spleen. |
| Signaling_pathway | Organismal Systems >> Immune system >> Neutrophil extracellular trap formation |
| Research Areas | >>Neutrophil extracellular trap formation; / >>Bile secretion |
| Function | Domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,Function:Forms a channel with a broad specificity. Mediates passage of a wide variety of non-charged solutes including carbamides, polyols, purines, and pyrimidines in a phloretin- and mercury-sensitive manner, whereas amino acids, cyclic sugars, Na(+), K(+), Cl(-), and deprotonated monocarboxylates are excluded. Also permeable to urea but not to glycerol.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family.,tissue specificity:Highly expressed in peripheral leukocytes. Also expressed in liver, lung, and spleen., |
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