Name: ARC Polyclonal Antibody
SKU: WP2681
Price: 268 USD
Availability: InStock

ARC Polyclonal Antibody

Ucallm_WP2681-50

Price range: $268.00 through $328.00

Size

100μl

50μl

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SKU: WP2681-100

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Product details

Background:

function:Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors., similarity:Belongs to the ARC/ARG3.1 family., subcellular location:Associated with the cell cortex of neuronal soma and dendrites. Enriched in postsynaptic density of dendritic spines. Associated with the sperm tail., subunit:Interacts with SH3GL1/endophilin-2, SH3GL3/endophilin-3 and DNM2/DYN2.,

Specifications

Target	ARC
Reactivity	Human, Mouse, Rat
Applications	WB, ELISA
MW(Calculated)
MW(Observed)	43kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Modification
Recommended Dilution Ratio	WB 1:500-2000; ELISA 1:5000-20000
Formulation	Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Source
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human protein . at AA range: 70-150
Sequence
Specificity	ARC Polyclonal Antibody detects endogenous levels of protein.
Gene Name	ARC KIAA0278
Protein Name	Activity-regulated cytoskeleton-associated protein (ARC/ARG3.1) (Activity-regulated gene 3.1 protein homolog) (Arg3.1)
Other Name
Species	Human
Gene ID-1	23237
Uniprot	Q7LC44,
Species.1	Mouse
Gene ID-2
Uniprot.1	Q9WV31,
Species.2	Rat
Gene ID-3
Uniprot.2	Q63053
Organism-4
Gene ID-4
SwissProt-4
Background	function:Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors.,similarity:Belongs to the ARC/ARG3.1 family.,subcellular location:Associated with the cell cortex of neuronal soma and dendrites. Enriched in postsynaptic density of dendritic spines. Associated with the sperm tail.,subunit:Interacts with SH3GL1/endophilin-2, SH3GL3/endophilin-3 and DNM2/DYN2.,
Cellular Localization	Extracellular vesicle membrane; Lipid-anchor . Cell junction, synapse, postsynaptic cell membrane; Lipid-anchor . Cell junction, synapse . Cell junction, synapse, postsynaptic density . Early endosome membrane . Cell projection, dendrite . Cytoplasm, cytoskeleton . Cytoplasm, cell cortex . Cell projection, dendritic spine . Cytoplasmic vesicle, secretory vesicle, acrosome . Forms virion-like extracellular vesicles that are released from neurons. Enriched in postsynaptic density of dendritic spines. Targeted to inactive synapses following interaction with CAMK2B in the kinase inactive state. Accumulation at weaker synapses may be required to prevent their undesired enhancement. Associated with the cell cortex of neuronal soma and dendrites (By similarity). Associated with the sperm tail (By similarity). .
Tissue Expression	Brain,Forebrain,Uterus,
Signaling_pathway
Research Areas	>>Amphetamine addiction
Function	Function:Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors.,similarity:Belongs to the ARC/ARG3.1 family.,subcellular location:Associated with the cell cortex of neuronal soma and dendrites. Enriched in postsynaptic density of dendritic spines. Associated with the sperm tail.,subunit:Interacts with SH3GL1/endophilin-2, SH3GL3/endophilin-3 and DNM2/DYN2.,
RRID

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ARC Polyclonal Antibody

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Specifications

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ARC Polyclonal Antibody

Product details

Specifications

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