Product details
Background:
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- Please choose product options by visiting GAG2E rabbit pAb.
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- Please choose product options by visiting ARD1B rabbit pAb.
ARD1A rabbit pAb
Ucallm_WP7171-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | NAA10 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 26kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ARD1A |
| Specificity | This antibody detects endogenous levels of ARD1A at Human, Mouse |
| Gene Name | NAA10 ARD1 ARD1A TE2 |
| Protein Name | N-alpha-acetyltransferase 10 (N-terminal acetyltransferase complex ARD1 subunit homolog A) (NatA catalytic subunit) |
| Other Name | |
| Species | Human |
| Gene ID | 8260 |
| Uniprot | P41227, |
| Species.1 | Mouse |
| Gene ID.1 | 56292 |
| Uniprot.1 | Q9QY36 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Nucleus . Also present in the free cytosolic and cytoskeleton-bound polysomes. . |
| Tissue Expression | Ubiquitous. |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalytic subunit of N-terminal acetyltransferase complexes which display alpha (N-terminal) acetyltransferase activity . Acetylates amino termini that are devoid of initiator methionine . The alpha (N-terminal) acetyltransferase activity may be important for vascular, hematopoietic and neuronal growth and development. Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation . Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration . Acetylates, and stabilizes TSC2, thereby repressing mTOR activity and suppressing cancer development . Acetylates HSPA1A and HSPA1B at 'Lys-77' which enhances its chaperone activity and leads to preferential binding to co-chaperone HOPX . Acetylates HIST1H4A . Acts as a negative regulator of sister chromatid cohesion during mitosis . |
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