ARHGAP11A Polyclonal Antibody
Ucallm_WP11116-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a member of the Rho GTPase activating protein family. In response to DNA damage, the encoded protein interacts with the p53 tumor suppressor protein and stimulates its tetramerization, which results in cell-cycle arrest and apoptosis. A chromosomal deletion that includes this gene is one cause of Prader-Willi syndrome, and an intronic variant of this gene may be associated with sleep duration in children. This gene is highly expressed in colon cancers and in a human basal-like breast cancer cell line. [provided by RefSeq, Sep 2016],
Specifications
| Size | 50μL/100μL |
| Target | ARHGAP11A |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 110kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ARHGAP11A. AA range:471-520 |
| Specificity | ARHGAP11A Polyclonal Antibody detects endogenous levels of ARHGAP11A protein. |
| Gene Name | ARHGAP11A |
| Protein Name | Rho GTPase-activating protein 11A |
| Other Name | ARHGAP11A; / KIAA0013; / Rho GTPase-activating protein 11A; / Rho-type GTPase-activating protein 11A |
| Species | Human |
| Gene ID | 9824 |
| Uniprot | Q6P4F7, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q80Y19 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Bone marrow,Epithelium,Eye,Testis,Uterus, |
| Signaling_pathway | |
| Research Areas | |
| Function | similarity:Contains 1 Rho-GAP domain., |
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