Price range: $268.00 through $328.00
Background:
This gene encodes a tumor suppressor related to the ADP-ribosylation factor (ARF) family of proteins. The encoded protein may play a role in apoptosis in a caspase-dependent manner. Polymorphisms in this gene have been associated with some familial cancers. [provided by RefSeq, May 2010],
| Size | 50μL/100μL |
| Target | ARL11 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 21kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 140-220 |
| Specificity | ARL11 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | ARL11 ARLTS1 |
| Protein Name | ADP-ribosylation factor-like protein 11 (ADP-ribosylation factor-like tumor suppressor protein 1) |
| Other Name | |
| Species | Human |
| Gene ID | 115761 |
| Uniprot | Q969Q4, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q6P3A9, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q5BK71 |
| Cellular Localization | intracellular, |
| Tissue Expression | Expressed in lung and leukocytes. |
| Signaling_pathway | |
| Research Areas | |
| Function | Disease:Defects in ARL11 may be a cause of susceptibility to chronic lymphocytic leukemia (CLL) [MIM:151400].,Function:May play a role in apoptosis. May act as a tumor suppressor.,similarity:Belongs to the small GTPase superfamily. Arf family.,tissue specificity:Expressed in lung and leukocytes., |
