SKU: WP11152 Categories: ,

Arylsulfatase I Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP11152-100
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Product details

Background:

This gene encodes a protein that belongs to a large family of sulfatases that hydrolyze sulfate esters and sulfamates. Members of this family play a role in several cellular processes, including hormone synthesis, cell signaling in development and degradation of macromolecules. The protein encoded by this gene is thought to be secreted, and to function in extracellular space. [provided by RefSeq, Jul 2016],

Specifications

Size50μL/100μL
TargetArylsulfatase I
ReactivityHuman, Monkey
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)64kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human ARSI. AA range:311-360
SpecificityArylsulfatase I Polyclonal Antibody detects endogenous levels of Arylsulfatase I protein.
Gene NameARSI
Protein NameArylsulfatase I
Other NameARSI; / Arylsulfatase I; / ASI
SpeciesHuman
Gene ID340075
UniprotQ5FYB1,
Species.1Mouse
Gene ID.1
Uniprot.1Q32KI9
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationSecreted . Endoplasmic reticulum . Localized in the intracellular granular structures.
Tissue ExpressionExpressed in placenta, in embryonic stem cells, fetal eyes and lens.
Signaling_pathway
Research Areas
Functioncofactor:Binds 1 calcium ion per subunit.,PTM:The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.,similarity:Belongs to the sulfatase family.,
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