Price range: $268.00 through $328.00
Background:
This gene belongs to the amiloride-sensitive Na+ channel and degenerin (NaC/DEG) family, members of which have been identified in many animal species ranging from the nematode to human. The amiloride-sensitive Na(+) channel encoded by this gene is primarily expressed in the small intestine, however, its exact function is not known. [provided by RefSeq, Jul 2008],
| Target | ASIC5 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 56kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Modification | |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Purity | |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ASIC5 AA range: 412-462 |
| Sequence | |
| Specificity | This antibody detects endogenous levels of ASIC5 at Human/Mouse/Rat |
| Gene Name | ASIC5 ACCN5 HINAC |
| Protein Name | ASIC5 |
| Other Name | |
| Species | Human |
| Gene ID-1 | 51802 |
| Uniprot | Q9NY37, |
| Species.1 | Mouse |
| Gene ID-2 | 58170 |
| Uniprot.1 | Q9R0Y1, |
| Species.2 | Rat |
| Gene ID-3 | 63866 |
| Uniprot.2 | Q9R0W5 |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Background | This gene belongs to the amiloride-sensitive Na+ channel and degenerin (NaC/DEG) family, members of which have been identified in many animal species ranging from the nematode to human. The amiloride-sensitive Na(+) channel encoded by this gene is primarily expressed in the small intestine, however, its exact function is not known. [provided by RefSeq, Jul 2008], |
| Cellular Localization | Cell membrane; Multi-pass membrane protein . |
| Tissue Expression | Detected in small intestine, duodenum and jejunum. Detected at very low levels in testis and rectum. |
| Signaling_pathway | Organismal Systems >> Sensory system >> Inflammatory mediator regulation of TRP channels |
| Research Areas | >>Inflammatory mediator regulation of TRP channels |
| Function | Function:Cation channel that gives rise to very low constitutive currents in the absence of activation. The activated channel exhibits selectivity for sodium, and is inhibited by amiloride.,similarity:Belongs to the amiloride-sensitive sodium channel family.,subunit:Homotetramer or heterotetramer.,tissue specificity:Detected in small intestine, duodenum and jejunum. Detected at very low levels in testis and rectum., |
| RRID |
