Product details
Background:
ASPRV1 rabbit pAb
Ucallm_WP8533-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | ASPRV1 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 38kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ASPRV1 |
| Specificity | This antibody detects endogenous levels of ASPRV1 at Human, Mouse |
| Gene Name | ASPRV1 SASP |
| Protein Name | Retroviral-like aspartic protease 1 (Skin-specific retroviral-like aspartic protease) (SASPase) (Skin aspartic protease) (TPA-inducible aspartic proteinase-like protein) (TAPS) |
| Other Name | |
| Species | Human |
| Gene ID | 151516 |
| Uniprot | Q53RT3, |
| Species.1 | Mouse |
| Gene ID.1 | 67855 |
| Uniprot.1 | Q09PK2 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Membrane; Single-pass membrane protein . |
| Tissue Expression | Expressed primarily in the granular layer of the epidermis and inner root sheath of hair follicles. In psoriatic skin, expressed throughout the stratum corneum. In ulcerated skin, expressed in the stratum granulosum of intact epidermis but almost absent from ulcerated regions. Expressed in differentiated areas of squamous cell carcinomas but not in undifferentiated tumors. |
| Signaling_pathway | |
| Research Areas | |
| Function | Protease responsible for filaggrin processing, essential for the maintenance of a proper epidermis organization. |
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