ATCAY rabbit pAb
Ucallm_WP17352-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a neuron-restricted protein that contains a CRAL-TRIO motif common to proteins that bind small lipophilic molecules. Mutations in this gene are associated with cerebellar ataxia, Cayman type. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | ATCAY |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 41kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ATCAY AA range: 69-119 |
| Specificity | This antibody detects endogenous levels of ATCAY at Human/Mouse/Rat |
| Gene Name | ATCAY KIAA1872 |
| Protein Name | ATCAY |
| Other Name | |
| Species | Human |
| Gene ID | 85300 |
| Uniprot | Q86WG3, |
| Species.1 | Mouse |
| Gene ID.1 | 16467 |
| Uniprot.1 | Q8BHE3, |
| Species.2 | Rat |
| Gene ID.2 | 362826 |
| Uniprot.2 | Q1M168 |
| Cellular Localization | Cell projection, axon . Cell projection, dendrite . Cell junction, synapse, presynapse . Mitochondrion . Cell projection, growth cone . Cytoplasm . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Disease:Defects in ATCAY are the cause of cerebellar ataxia, cayman type (ATCAY) [MIM:601238]. ATCAY is found in a population isolate on Grand Cayman Island and causes a marked psychomotor retardation and prominent nonprogressive cerebellar dysfunction including nystagmus, intention tremor, dysarthria, and wide-based ataxic gait. Hypotonia is present from early childhood.,Domain:The CRAL-TRIO domain is known to bind small hydrophobic molecules.,similarity:Contains 1 CRAL-TRIO domain., |
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