Price range: $268.00 through $328.00
Background:
This intronless gene encodes a member of the basic helix-loop-helix family of transcription factors, with similarity to Drosophila atonal gene that controls photoreceptor development. Studies in mice suggest that this gene plays a central role in retinal ganglion cell and optic nerve formation. Mutations in this gene are associated with nonsyndromic congenital retinal nonattachment. [provided by RefSeq, Dec 2011],
| Size | 50μL/100μL |
| Target | ATOH7 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 16kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | ATOH7 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | ATOH7 ATH5 BHLHA13 |
| Protein Name | Protein atonal homolog 7 (Class A basic helix-loop-helix protein 13) (bHLHa13) (Helix-loop-helix protein hATH-5) (hATH5) |
| Other Name | |
| Species | Human |
| Gene ID | 220202 |
| Uniprot | Q8N100, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9Z2E5 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Perikaryon . Cell projection, axon . |
| Tissue Expression | Eye, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Transcription factor involved in the differentiation of retinal ganglion cells.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain., |
