SKU: WP11207 Categories: ,

ATP5L2 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP11207-100
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Product details

Background:

function:Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) – containing the extramembraneous catalytic core, and F(0) – containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane., similarity:Belongs to the ATPase g subunit family., subunit:F-type ATPases have 2 components, CF(1) – the catalytic core – and CF(0) – the membrane proton channel. CF(0) seems to have nine subunits: a, b, c, d, e, f, g, F6 and 8 (or A6L).,

Specifications

Size50μL/100μL
TargetATP5L2
ReactivityHuman
ApplicationsWB, IF, ELISA
MW(Calculated)
MW(Observed)20kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human ATP5L2. AA range:51-100
SpecificityATP5L2 Polyclonal Antibody detects endogenous levels of ATP5L2 protein.
Gene NameATP5L2
Protein NameATP synthase subunit g 2 mitochondrial
Other NameATP5L2; / ATP5K2; / ATP synthase subunit g 2; / mitochondrial; / ATPase subunit g 2
SpeciesHuman
Gene ID267020
UniprotQ7Z4Y8
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationMitochondrion membrane .
Tissue ExpressionLiver,
Signaling_pathway
Research Areas
FunctionFunction:Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.,similarity:Belongs to the ATPase g subunit family.,subunit:F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) seems to have nine subunits: a, b, c, d, e, f, g, F6 and 8 (or A6L).,
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