Product details
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ATP6V0A1 rabbit pAb
Ucallm_WP6290-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | ATP6V0A1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 92kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ATP6V0A1 |
| Specificity | This antibody detects endogenous levels of ATP6V0A1 at Human, Mouse,Rat |
| Gene Name | ATP6V0A1 ATP6N1 ATP6N1A VPP1 |
| Protein Name | V-type proton ATPase 116 kDa subunit a isoform 1 (V-ATPase 116 kDa isoform a1) (Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit) (Vacuolar adenosine triphosphatase subunit Ac116) (Vacuolar proton pump subunit 1) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1) |
| Other Name | |
| Species | Human |
| Gene ID | 535 |
| Uniprot | Q93050, |
| Species.1 | Mouse |
| Gene ID.1 | 11975 |
| Uniprot.1 | Q9Z1G4, |
| Species.2 | Rat |
| Gene ID.2 | 29757 |
| Uniprot.2 | P25286 |
| Cellular Localization | Cytoplasmic vesicle, clathrin-coated vesicle membrane; Multi-pass membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. . |
| Tissue Expression | |
| Signaling_pathway | Cellular Processes >> Transport and catabolism >> Phagosome;Cellular Processes >> Transport and catabolism >> Lysosome;Organismal Systems >> Nervous system >> Synaptic vesicle cycle;Human Diseases >> Immune disease >> Rheumatoid arthritis |
| Research Areas | |
| Function | Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons . V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). Required for assembly and activity of the vacuolar ATPase (By similarity). |
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