Product details
Background:
AXIN2 rabbit pAb
Ucallm_WP6007-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | AXIN2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 93kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human AXIN2 |
| Specificity | This antibody detects endogenous levels of AXIN2 at Human, Mouse,Rat |
| Gene Name | AXIN2 |
| Protein Name | Axin-2 (Axin-like protein) (Axil) (Axis inhibition protein 2) (Conductin) |
| Other Name | |
| Species | Human |
| Gene ID | 8313 |
| Uniprot | Q9Y2T1, |
| Species.1 | Mouse |
| Gene ID.1 | 12006 |
| Uniprot.1 | O88566, |
| Species.2 | Rat |
| Gene ID.2 | 29134 |
| Uniprot.2 | O70240 |
| Cellular Localization | Cytoplasm . |
| Tissue Expression | Expressed in brain and lymphoblast. |
| Signaling_pathway | Cellular Processes >> Cellular community - eukaryotes >> Signaling pathways regulating pluripotency of stem cells;Human Diseases >> Cancer: overview >> Pathways in cancer;Human Diseases >> Cancer: specific types >> Colorectal cancer;Human Diseases >> Cancer: specific types >> Hepatocellular carcinoma;Human Diseases >> Cancer: specific types >> Gastric cancer;Human Diseases >> Cancer: specific types >> Basal cell carcinoma;Human Diseases >> Cancer: specific types >> Endometrial cancer;Human Diseases >> Cancer: specific types >> Breast cancer;Human Diseases >> Neurodegenerative disease >> Alzheimer disease;Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases;Environmental Information Processing >> Signal transduction >> Wnt signaling pathway;Environmental Information Processing >> Signal transduction >> Hippo signaling pathway |
| Research Areas | |
| Function | Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta-catenin and APC by GSK3B. |
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