The protein encoded by this gene is a plasma membrane anion exchange protein. The encoded protein has been found in brain, heart, kidney, small intestine, and lung. [provided by RefSeq, May 2016],
Specifications
Size
50μL/100μL
Target
B3A3
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
MW(Calculated)
MW(Observed)
135kD
Host Species
Rabbit
Isotype
IgG
Conjugate/Modification
Unmodified
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human protein . at AA range: 420-500
Specificity
B3A3 Polyclonal Antibody detects endogenous levels of protein.
Gene Name
SLC4A3 AE3
Protein Name
Anion exchange protein 3 (AE 3) (Anion exchanger 3) (CAE3/BAE3) (Cardiac/brain band 3-like protein) (Neuronal band 3-like protein) (Solute carrier family 4 member 3)
Other Name
Species
Human
Gene ID
6508
Uniprot
P48751,
Species.1
Mouse
Gene ID.1
Uniprot.1
P16283,
Species.2
Rat
Gene ID.2
Uniprot.2
P23348
Cellular Localization
Membrane; Multi-pass membrane protein.
Tissue Expression
Both BAE3 and CAE3 are expressed in failing ventricle.
Signaling_pathway
Research Areas
Function
Alternative products:Additional isoforms seem to exist,Function:Plasma membrane anion exchange protein of wide distribution. Mediates at least a part of the Cl(-)/HCO3(-) exchange in cardiac myocytes. Both BAE3 and CAE3 forms transport Cl(-).,similarity:Belongs to the anion exchanger (TC 2.A.31) family.,tissue specificity:Both BAE3 and CAE3 are expressed in failing ventricle.,