Product details
Background:
The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes. [provided by RefSeq, Jun 2011],
METK2 rabbit pAb
Ucallm_WP16960-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | METK2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA, IHC |
| MW(Calculated) | 43kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human METK2 AA range: 294-344 |
| Specificity | This antibody detects endogenous levels of METK2 at Human/Mouse/Rat |
| Gene Name | MAT2A AMS2 MATA2 |
| Protein Name | METK2 |
| Other Name | |
| Species | Human |
| Gene ID | 4144 |
| Uniprot | P31153, |
| Species.1 | Mouse |
| Gene ID.1 | 232087 |
| Uniprot.1 | Q3THS6, |
| Species.2 | Rat |
| Gene ID.2 | 171347 |
| Uniprot.2 | P18298 |
| Cellular Localization | cytosol,methionine adenosyltransferase complex, |
| Tissue Expression | Detected in kidney. |
| Signaling_pathway | |
| Research Areas | >>Cysteine and methionine metabolism; / >>Metabolic pathways; / >>Biosynthesis of amino acids; / >>Biosynthesis of cofactors |
| Function | Catalytic activity:ATP + L-methionine + H(2)O = phosphate + diphosphate + S-adenosyl-L-methionine.,cofactor:Binds 1 potassium ion per subunit.,cofactor:Binds 2 divalent ions per subunit. Magnesium or cobalt.,Function:Catalyzes the formation of S-adenosylmethionine from methionine and ATP.,pathway:Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.,PTM:The alpha' subunit is a post-translationally modified version of MAT2A.,similarity:Belongs to the AdoMet synthetase family.,subunit:Heterotetramer composed of 2 catalytic alpha subunits (alpha and alpha') (MAT2A) and 1 copy of beta subunit (MAT2B)., |
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