Price range: $268.00 through $328.00
Background:
This gene encodes a member of the beta-1, 3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It prefers the substrate of lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2016],
| Size | 50μL/100μL |
| Target | B3GN2 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 44kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human B3GN2 AA range: 190-240 |
| Specificity | This antibody detects endogenous levels of B3GN2 at Human/Mouse |
| Gene Name | B3GNT2 B3GALT7 B3GNT1 |
| Protein Name | B3GN2 |
| Other Name | |
| Species | Human |
| Gene ID | 10678 |
| Uniprot | Q9NY97, |
| Species.1 | Mouse |
| Gene ID.1 | 53625 |
| Uniprot.1 | Q9Z222 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Golgi apparatus membrane; Single-pass type II membrane protein . |
| Tissue Expression | Ubiquitous. |
| Signaling_pathway | |
| Research Areas | >>Glycosaminoglycan biosynthesis - keratan sulfate; / >>Glycosphingolipid biosynthesis - lacto and neolacto series; / >>Metabolic pathways |
| Function | Catalytic activity:UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-R.,Caution:Was indicated as B3Gal-T6 in submitted DNA entries.,cofactor:Manganese.,Function:Can initiate the synthesis or the elongation of the linear poly-N-acetyllactosaminoglycans.,Function:Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains.,online information:GlycoGene database,online information:N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase,online information:UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 31 family.,tissue specificity:In the adult, highly expressed in heart, brain, skeletal muscle and kidney and to a lesser extent in placenta, pancreas, spleen, prostate, testis, ovary, small intestine and colon. Very weak expression in lung, liver, thymus and peripheral blood leukocytes. In fetal highly expressed in brain and kidney and to a lesser extent in lung and liver., |
