BAGE4 Polyclonal Antibody
Product details
Background:
function:Unknown. Candidate gene encoding tumor antigens., miscellaneous:The ancestral BAGE gene was generated by juxtacentromeric reshuffling of the MLL3 gene. The BAGE family was expanded by juxtacentromeric movement and/or acrocentric exchanges. BAGE family is composed of expressed genes that map to the juxtacentromeric regions of chromosomes 13 and 21 and of unexpressed gene fragments that scattered in the juxtacentromeric regions of several chromosomes, including chromosomes 9, 13, 18 and 21., similarity:Belongs to the BAGE family., tissue specificity:Not expressed in normal tissues except in testis. Expressed in 22% of melanomas, in bladder and lung carcinomas., tissue specificity:Not expressed in normal tissues except in testis. Expressed in melanoma, bladder and lung carcinomas.,
Specifications
| Size | 50μL/100μL |
| Target | BAGE4 |
| Reactivity | Human |
| Applications | IHC, IF, ELISA |
| MW(Calculated) | 4kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human BAGE4. AA range:9-58 |
| Specificity | BAGE4 Polyclonal Antibody detects endogenous levels of BAGE4 protein. |
| Gene Name | BAGE4 |
| Protein Name | B melanoma antigen 4 |
| Other Name | BAGE4; / MLL3P; / B melanoma antigen 4; / Cancer/testis antigen 2.4; / CT2.4 |
| Species | Human |
| Gene ID | 85317 |
| Uniprot | Q86Y28 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted . |
| Tissue Expression | Not expressed in normal tissues except in testis. Expressed in melanoma, bladder and lung carcinomas. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Unknown. Candidate gene encoding tumor antigens.,miscellaneous:The ancestral BAGE gene was generated by juxtacentromeric reshuffling of the MLL3 gene. The BAGE family was expanded by juxtacentromeric movement and/or acrocentric exchanges. BAGE family is composed of expressed genes that map to the juxtacentromeric regions of chromosomes 13 and 21 and of unexpressed gene fragments that scattered in the juxtacentromeric regions of several chromosomes, including chromosomes 9, 13, 18 and 21.,similarity:Belongs to the BAGE family.,tissue specificity:Not expressed in normal tissues except in testis. Expressed in 22% of melanomas, in bladder and lung carcinomas.,tissue specificity:Not expressed in normal tissues except in testis. Expressed in melanoma, bladder and lung carcinomas., |





