SKU: WP11241 Categories: ,

BAGE4 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP11241-100
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Product details

Background:

function:Unknown. Candidate gene encoding tumor antigens., miscellaneous:The ancestral BAGE gene was generated by juxtacentromeric reshuffling of the MLL3 gene. The BAGE family was expanded by juxtacentromeric movement and/or acrocentric exchanges. BAGE family is composed of expressed genes that map to the juxtacentromeric regions of chromosomes 13 and 21 and of unexpressed gene fragments that scattered in the juxtacentromeric regions of several chromosomes, including chromosomes 9, 13, 18 and 21., similarity:Belongs to the BAGE family., tissue specificity:Not expressed in normal tissues except in testis. Expressed in 22% of melanomas, in bladder and lung carcinomas., tissue specificity:Not expressed in normal tissues except in testis. Expressed in melanoma, bladder and lung carcinomas.,

Specifications

Size50μL/100μL
TargetBAGE4
ReactivityHuman
ApplicationsIHC, IF, ELISA
MW(Calculated)4kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioIHC 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human BAGE4. AA range:9-58
SpecificityBAGE4 Polyclonal Antibody detects endogenous levels of BAGE4 protein.
Gene NameBAGE4
Protein NameB melanoma antigen 4
Other NameBAGE4; / MLL3P; / B melanoma antigen 4; / Cancer/testis antigen 2.4; / CT2.4
SpeciesHuman
Gene ID85317
UniprotQ86Y28
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationSecreted .
Tissue ExpressionNot expressed in normal tissues except in testis. Expressed in melanoma, bladder and lung carcinomas.
Signaling_pathway
Research Areas
FunctionFunction:Unknown. Candidate gene encoding tumor antigens.,miscellaneous:The ancestral BAGE gene was generated by juxtacentromeric reshuffling of the MLL3 gene. The BAGE family was expanded by juxtacentromeric movement and/or acrocentric exchanges. BAGE family is composed of expressed genes that map to the juxtacentromeric regions of chromosomes 13 and 21 and of unexpressed gene fragments that scattered in the juxtacentromeric regions of several chromosomes, including chromosomes 9, 13, 18 and 21.,similarity:Belongs to the BAGE family.,tissue specificity:Not expressed in normal tissues except in testis. Expressed in 22% of melanomas, in bladder and lung carcinomas.,tissue specificity:Not expressed in normal tissues except in testis. Expressed in melanoma, bladder and lung carcinomas.,
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