Product details
Background:
Band 3/AE1 rabbit pAb
Ucallm_WP7234-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | SLC4A1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 100kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human Band 3/AE1 |
| Specificity | This antibody detects endogenous levels of Band 3/AE1 at Human, Mouse,Rat |
| Gene Name | SLC4A1 AE1 DI EPB3 |
| Protein Name | Band 3 anion transport protein (Anion exchange protein 1) (AE 1) (Anion exchanger 1) (Solute carrier family 4 member 1) (CD antigen CD233) |
| Other Name | |
| Species | Human |
| Gene ID | 6521 |
| Uniprot | P02730, |
| Species.1 | Mouse |
| Gene ID.1 | 20533 |
| Uniprot.1 | P04919, |
| Species.2 | Rat |
| Gene ID.2 | 24779 |
| Uniprot.2 | P23562 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein . Basolateral cell membrane; Multi-pass membrane protein . Detected in the erythrocyte cell membrane and on the basolateral membrane of alpha-intercalated cells in the collecting duct in the kidney. . |
| Tissue Expression | Detected in erythrocytes (at protein level).; [Isoform 2]: Expressed in kidney (at protein level). |
| Signaling_pathway | |
| Research Areas | |
| Function | Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Major integral membrane glycoprotein of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride-bicarbonate exchange in the kidney, and is required for normal acidification of the urine. |
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