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Bc10 Polyclonal Antibody
Ucallm_WP11254-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a protein that reduces cell growth by stimulating apoptosis. Alternative splicing and the use of alternative promoters result in multiple transcript variants encoding the same protein. This gene is imprinted in brain where different transcript variants are expressed from each parental allele. Transcript variants initiating from the upstream promoter are expressed preferentially from the maternal allele, while transcript variants initiating downstream of the interspersed NNAT gene (GeneID:4826) are expressed from the paternal allele. Transcripts at this locus may also undergo A to I editing, resulting in amino acid changes at three positions in the N-terminus of the protein. [provided by RefSeq, Nov 2015],
Specifications
| Size | 50μL/100μL |
| Target | Bc10 |
| Reactivity | Human, Mouse, Rat |
| Applications | IF, ELISA |
| MW(Calculated) | 10kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications; |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human BLCAP. AA range:38-87 |
| Specificity | Bc10 Polyclonal Antibody detects endogenous levels of Bc10 protein. |
| Gene Name | BLCAP |
| Protein Name | Bladder cancer-associated protein |
| Other Name | BLCAP; / BC10; / Bladder cancer-associated protein; / Bladder cancer 10 kDa protein; / Bc10 |
| Species | Human |
| Gene ID | 10904 |
| Uniprot | P62952, |
| Species.1 | Mouse |
| Gene ID.1 | 53619 |
| Uniprot.1 | P62951, |
| Species.2 | Rat |
| Gene ID.2 | 171113 |
| Uniprot.2 | P62950 |
| Cellular Localization | Membrane; Multi-pass membrane protein . |
| Tissue Expression | Ubiquitous. Expressed in cervical tissues. Down-regulated in bladder invasive carcinoma, renal cell carcinoma and in primary cervical carcinoma. |
| Signaling_pathway | |
| Research Areas | |
| Function | similarity:Belongs to the BLCAP family.,tissue specificity:Expressed in cervical tissues. Down-regulated during bladder cancer progression and in most cervical carcinomas., |
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