Price range: $268.00 through $328.00
Background:
Component of the fork protection machinery required to protect stalled/damaged replication forks from uncontrolled DNA2-dependent resection. Acts by stabilizing RAD51 at stalled replication forks and protecting RAD51 nucleofilaments from the antirecombinogenic activities of FBXO18/FBH1 and BLM.
| Size | 50μL/100μL |
| Target | BD1L1 |
| Reactivity | Human |
| Applications | IHC, IF |
| MW(Calculated) | |
| MW(Observed) | 335kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:50-300; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 1280-1360 |
| Specificity | BD1L1 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | BOD1L1 BOD1L FAM44A KIAA1327 |
| Protein Name | Biorientation of chromosomes in cell division protein 1-like 1 (Protein FAM44A) |
| Other Name | |
| Species | Human |
| Gene ID | 259282 |
| Uniprot | Q8NFC6 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Chromosome . Localizes at replication forks: following DNA damage, localizes to damaged replication forks undergoing resection. . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function |
