function:May sustain the structure of the postsynaptic density (PSD)., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., subunit:Interacts with DLG4 and DLGAP1 and forms a ternary complex.,
Specifications
Size
50μL/100μL
Target
BEGAIN
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)
65kD
Host Species
Rabbit
Isotype
IgG
Conjugate/Modification
Unmodified
Recommended Dilution Ratio
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
The antiserum was produced against synthesized peptide derived from human BEGIN. AA range:511-560
Specificity
BEGAIN Polyclonal Antibody detects endogenous levels of BEGAIN protein.
Gene Name
BEGAIN
Protein Name
Brain-enriched guanylate kinase-associated protein
Other Name
BEGAIN; / KIAA1446; / Brain-enriched guanylate kinase-associated protein
Species
Human
Gene ID
57596
Uniprot
Q9BUH8,
Species.1
Mouse
Gene ID.1
380785
Uniprot.1
Q68EF6,
Species.2
Rat
Gene ID.2
79146
Uniprot.2
O88881
Cellular Localization
Cytoplasm . Membrane; Peripheral membrane protein .
Tissue Expression
Amygdala,Brain,Epithelium,
Signaling_pathway
Research Areas
Function
Function:May sustain the structure of the postsynaptic density (PSD).,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subunit:Interacts with DLG4 and DLGAP1 and forms a ternary complex.,