BEX2 rabbit pAb
Ucallm_WP16713-50
Price range: $268.00 through $328.00
Product details
Background:
This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009],
Specifications
| Size | 50μL/100μL |
| Target | BEX2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 14kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human BEX2 AA range: 28-78 |
| Specificity | This antibody detects endogenous levels of BEX2 at Human/Mouse/Rat |
| Gene Name | BEX2 |
| Protein Name | BEX2 |
| Other Name | |
| Species | Human |
| Gene ID | 84707 |
| Uniprot | Q9BXY8, |
| Species.1 | Mouse |
| Gene ID.1 | 12069 |
| Uniprot.1 | Q9WTZ8, |
| Species.2 | Rat |
| Gene ID.2 | 363498 |
| Uniprot.2 | Q3MKQ1 |
| Cellular Localization | Cytoplasm . Nucleus . |
| Tissue Expression | Expressed in central nervous system, with high level in pituitary, cerebellum and temporal lobe. Widely expressed in breast cancer cell lines. |
| Signaling_pathway | |
| Research Areas | |
| Function | Caution:Was named BEX1 by some authors.,similarity:Belongs to the BEX family.,subunit:Interacts with OMP (By similarity). Interacts with LMO2, possibly leading to regulate the transcriptional activity of a DNA-binding complex containing LMO2.,tissue specificity:Expressed in central nervous system, with high level in pituitary, cerebellum and temporal lobe., |
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