Name: BinCARD Polyclonal Antibody
SKU: WP11278
Price: 268 USD
Availability: InStock

BinCARD Polyclonal Antibody

Ucallm_WP11278-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP11278-100

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Product details

Background:

function:Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner., PTM:Isoform 2 is phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 1 CARD domain., subcellular location:Co-expression with BCL10 induced translocation from nucleus to cytosol., subunit:Associates with BCL10 by CARD-CARD interaction., tissue specificity:Expressed in ovary, testis, placenta, skeletal muscle, kidney, lung, heart and liver (at protein level). Expressed in thymus and brain.,

Specifications

Size	50μL/100μL
Target	BinCARD
Reactivity	Human, Mouse
Applications	IHC, IF, ELISA
MW(Calculated)	26kD
MW(Observed)
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human C9orf89. AA range:21-70
Specificity	BinCARD Polyclonal Antibody detects endogenous levels of BinCARD protein.
Gene Name	C9orf89
Protein Name	Bcl10-interacting CARD protein
Other Name	C9orf89; / Bcl10-interacting CARD protein; / BinCARD
Species	Human
Gene ID	84270
Uniprot	Q96LW7,
Species.1	Mouse
Gene ID.1	68480
Uniprot.1	Q9D1I2
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	[Isoform 1]: Nucleus . Coexpression with BCL10 induced translocation from nucleus to cytosol.; [Isoform 2]: Endoplasmic reticulum membrane; Single-pass membrane protein . Mitochondrion membrane; Single-pass membrane protein .
Tissue Expression	Expressed in ovary, testis, placenta, skeletal muscle, kidney, lung, heart and liver (at protein level). Expressed in thymus and brain.
Signaling_pathway
Research Areas
Function	Function:Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner.,PTM:Isoform 2 is phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 CARD domain.,subcellular location:Co-expression with BCL10 induced translocation from nucleus to cytosol.,subunit:Associates with BCL10 by CARD-CARD interaction.,tissue specificity:Expressed in ovary, testis, placenta, skeletal muscle, kidney, lung, heart and liver (at protein level). Expressed in thymus and brain.,

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BinCARD Polyclonal Antibody

Product details

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BinCARD Polyclonal Antibody

Product details

Specifications

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