Name: BMP-2 Polyclonal Antibody
SKU: WP15645
Price: 268 USD
Availability: InStock

BMP-2 Polyclonal Antibody

Ucallm_WP15645-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP15645-100

Enter the quantity you would like, or drag the panel to find the quantity and price that best for you

Bulk Quote Authorize OEM & ODM

Product details

Background:

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016],

Specifications

Size	50μL/100μL
Target	BMP-2
Reactivity	Human, Mouse, Rat
Applications	IF, WB, IHC, ELISA
MW(Calculated)
MW(Observed)	44kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	IF 1:50-200; WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:10000; Not yet tested in other applications; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from Bone morphogenetic protein 2 at AA range: 341-390
Specificity	BMP-2 Polyclonal Antibody detects endogenous levels of BMP-2 protein.
Gene Name	BMP2
Protein Name	Bone morphogenetic protein 2
Other Name	BMP2; / BMP2A; / Bone morphogenetic protein 2; / BMP-2; / Bone morphogenetic protein 2A; / BMP-2A
Species	Human
Gene ID	650
Uniprot	P12643,
Species.1	Mouse
Gene ID.1	12156
Uniprot.1	P21274,
Species.2	Rat
Gene ID.2	29373
Uniprot.2	P49001
Cellular Localization	Secreted.
Tissue Expression	Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.
Signaling_pathway	Human Diseases >> Cancer: overview >> Pathways in cancer;Human Diseases >> Cancer: specific types >> Basal cell carcinoma;Environmental Information Processing >> Signal transduction >> TGF-beta signaling pathway;Environmental Information Processing >> Signal transduction >> Hippo signaling pathway;Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
Research Areas	>>Cytokine-cytokine receptor interaction; / >>TGF-beta signaling pathway; / >>Hippo signaling pathway; / >>Pathways in cancer; / >>Basal cell carcinoma
Function	Function:Induces cartilage and bone formation.,online information:Bone morphogenetic protein 2 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked. Interacts with GREM2 (By similarity) and SOSTDC1.,tissue specificity:Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.,

Please login to post questions

BMP-2 Polyclonal Antibody

Product details

Specifications

About Us

Support

Order

Menu

BMP-2 Polyclonal Antibody

Product details

Specifications

Related products

U-Blot™ Universal Antibody Dilution Buffer

U-Blot® MMP7 Rabbit mAb

U-Blot® HDAC2 Rabbit mAb

U-Blot® GSK3 β (Phospho Ser9) Rabbit mAb

U-Blot® α smooth muscle actin Rabbit mAb

U-Blot® SQSTM1/p62 Rabbit mAb

Customer Reviews

Menu