BMP3B Polyclonal Antibody
Ucallm_WP0934-50
Price range: $268.00 through $328.00
Product details
Background:
growth differentiation factor 10(GDF10) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This promotes neural repair after stroke. Additionally, this protein may act as a tumor suppressor and reduced expression of this gene is associated with oral cancer. [provided by RefSeq, Jul 2016],
Specifications
| Size | 50μL/100μL |
| Target | BMP-3B |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 52kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein AA range: 421-470 |
| Specificity | BMP3B Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | GDF10 BMP3B |
| Protein Name | Bone morphogenetic protein 3B (BMP-3B) (Bone-inducing protein) (BIP) (Growth/differentiation factor 10) (GDF-10) |
| Other Name | |
| Species | Human |
| Gene ID | 2662 |
| Uniprot | P55107, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P97737, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | P55108 |
| Cellular Localization | Secreted . |
| Tissue Expression | Expressed in femur, brain, lung, skeletal muscle, pancreas and testis. |
| Signaling_pathway | Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction |
| Research Areas | >>Cytokine-cytokine receptor interaction |
| Function | similarity:Belongs to the TGF-beta family.,subunit:Homodimer or heterodimer .,tissue specificity:Expressed in femur, brain, lung, skeletal muscle, pancreas and testis., |
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