SKU: WP11296 Categories: ,

BNIP-2 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP11296-100
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Product details

Background:

This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],

Specifications

Size50μL/100μL
TargetBNIP-2
ReactivityHuman, Mouse
ApplicationsWB, IF, FC, ELISA
MW(Calculated)
MW(Observed)36kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IF 1:200-1:1000; Flow Cyt 1:200-1:400; ELISA 1:40000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human BNIP2. AA range:265-314
SpecificityBNIP-2 Polyclonal Antibody detects endogenous levels of BNIP-2 protein.
Gene NameBNIP2
Protein NameBCL2/adenovirus E1B 19 kDa protein-interacting protein 2
Other NameBNIP2; / NIP2; / BCL2/adenovirus E1B 19 kDa protein-interacting protein 2
SpeciesHuman
Gene ID663
UniprotQ12982,
Species.1Mouse
Gene ID.112175
Uniprot.1O54940
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm. Cytoplasm, perinuclear region. Localizes to the nuclear envelope region and to other cytoplasmic structures.
Tissue ExpressionEye,Platelet,
Signaling_pathway
Research Areas
FunctionFunction:Implicated in the suppression of cell death. Interacts with the BCL-2 and adenovirus E1B 19 kDa proteins.,similarity:Contains 1 CRAL-TRIO domain.,subcellular location:Localizes to the nuclear envelope region and to other cytoplasmic structures.,
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