Price range: $268.00 through $328.00
Background:
This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. The function of the encoded protein is not known. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | BRD3 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 90kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human BRD3. AA range:611-660 |
| Specificity | BRD3 Polyclonal Antibody detects endogenous levels of BRD3 protein. |
| Gene Name | BRD3 |
| Protein Name | Bromodomain-containing protein 3 |
| Other Name | BRD3; / KIAA0043; / RING3L; / Bromodomain-containing protein 3; / RING3-like protein |
| Species | Human |
| Gene ID | 8019 |
| Uniprot | Q15059, |
| Species.1 | Mouse |
| Gene ID.1 | 67382 |
| Uniprot.1 | Q8K2F0 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Detected on chromatin. . |
| Tissue Expression | Ubiquitous. |
| Signaling_pathway | |
| Research Areas | |
| Function | Disease:A chromosomal aberration involving BRD3 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15; 9)(q14; q34) with NUT which produces a BRD3-NUT fusion protein.,similarity:Contains 2 bromo domains.,tissue specificity:Ubiquitous., |
