Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human SYTL1 AA range: 333-383
Specificity
This antibody detects endogenous levels of SYTL1 at Human/Mouse
Gene Name
SYTL1 SLP1 SB146
Protein Name
SYTL1
Other Name
Synaptotagmin-like protein 1; / Exophilin-7; / Protein JFC1
Species
Human
Gene ID
84958
Uniprot
Q8IYJ3,
Species.1
Mouse
Gene ID.1
Uniprot.1
Q99N80
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cell membrane; Peripheral membrane protein; Cytoplasmic side . Peripheral membrane protein tightly bound to the cytoplasmic side of cellular membranes.
Tissue Expression
Highly expressed in bone marrow and lymphoid tissues. Detected at lower levels in cerebellum, occipital lobe, prostate, stomach, kidney, appendix, lung and trachea. Expressed in cytotoxic T-lymphocytes (CTL).
Signaling_pathway
Research Areas
Function
Function:May act as Rab effector protein and play a role in vesicle trafficking (By similarity). Binds phosphatidylinositol 3,4,5-triphosphate.,similarity:Contains 1 C2 domain.,similarity:Contains 1 RabBD (Rab-binding) domain.,similarity:Contains 2 C2 domains.,subcellular location:Peripheral membrane protein tightly bound to the cytoplasmic side of cellular membranes.,subunit:Monomer. Binds NRXN1. Binds RAB27A that has been activated by GTP-binding via its N-terminus (By similarity). Binds NCF2.,tissue specificity:Highly expressed in bone marrow and lymphoid tissues. Detected at lower levels in cerebellum, occipital lobe, prostate, stomach, kidney, appendix, lung and trachea.,