SKU: WP3509 Categories: ,

SYTL1 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP3509-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetSYTL1
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)
MW(Observed)60kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human SYTL1 AA range: 333-383
SpecificityThis antibody detects endogenous levels of SYTL1 at Human/Mouse
Gene NameSYTL1 SLP1 SB146
Protein NameSYTL1
Other NameSynaptotagmin-like protein 1; / Exophilin-7; / Protein JFC1
SpeciesHuman
Gene ID84958
UniprotQ8IYJ3,
Species.1Mouse
Gene ID.1
Uniprot.1Q99N80
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCell membrane; Peripheral membrane protein; Cytoplasmic side . Peripheral membrane protein tightly bound to the cytoplasmic side of cellular membranes.
Tissue ExpressionHighly expressed in bone marrow and lymphoid tissues. Detected at lower levels in cerebellum, occipital lobe, prostate, stomach, kidney, appendix, lung and trachea. Expressed in cytotoxic T-lymphocytes (CTL).
Signaling_pathway
Research Areas
FunctionFunction:May act as Rab effector protein and play a role in vesicle trafficking (By similarity). Binds phosphatidylinositol 3,4,5-triphosphate.,similarity:Contains 1 C2 domain.,similarity:Contains 1 RabBD (Rab-binding) domain.,similarity:Contains 2 C2 domains.,subcellular location:Peripheral membrane protein tightly bound to the cytoplasmic side of cellular membranes.,subunit:Monomer. Binds NRXN1. Binds RAB27A that has been activated by GTP-binding via its N-terminus (By similarity). Binds NCF2.,tissue specificity:Highly expressed in bone marrow and lymphoid tissues. Detected at lower levels in cerebellum, occipital lobe, prostate, stomach, kidney, appendix, lung and trachea.,
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