Price range: $268.00 through $328.00
Background:
The protein encoded by this gene was first identified by its ability to bind the adenovirus E1A protein. The protein localizes to the nucleus. It functions as a transcriptional repressor, and expression of E1A inhibits this repression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | BS69 |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC, IF, ELISA |
| MW(Calculated) | 66kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ZMY11. AA range:111-160 |
| Specificity | BS69 Polyclonal Antibody detects endogenous levels of BS69 protein. |
| Gene Name | ZMYND11 |
| Protein Name | Zinc finger MYND domain-containing protein 11 |
| Other Name | ZMYND11; / BS69; / Zinc finger MYND domain-containing protein 11; / Adenovirus 5 E1A-binding protein; / Protein BS69 |
| Species | Human |
| Gene ID | 10771 |
| Uniprot | Q15326, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q8R5C8 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Chromosome . Associates with chromatin and mitotic chromosomes. . |
| Tissue Expression | Ubiquitous. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Binds to the transactivation domain of the adenovirus type 5 E1A 32 kDa protein (289R) and inhibits its transactivating activity. May act as tumor suppressor through suppression of adenovirus replication.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 bromo domain.,similarity:Contains 1 MYND-type zinc finger.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 1 PWWP domain., |
