BTG2 rabbit pAb
Ucallm_WP6350-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | BTG2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 17kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human BTG2 |
| Specificity | This antibody detects endogenous levels of BTG2 at Human, Mouse,Rat |
| Gene Name | BTG2 PC3 |
| Protein Name | Protein BTG2 (BTG family member 2) (NGF-inducible anti-proliferative protein PC3) |
| Other Name | |
| Species | Human |
| Gene ID | 7832 |
| Uniprot | P78543, |
| Species.1 | Mouse |
| Gene ID.1 | 12227 |
| Uniprot.1 | Q04211, |
| Species.2 | Rat |
| Gene ID.2 | 29619 |
| Uniprot.2 | P27049 |
| Cellular Localization | |
| Tissue Expression | |
| Signaling_pathway | Genetic Information Processing >> Folding, sorting and degradation >> RNA degradation |
| Research Areas | |
| Function | Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Activates mRNA deadenylation in a CNOT6 and CNOT7-dependent manner. In vitro can inhibit deadenylase activity of CNOT7 and CNOT8. Involved in cell cycle regulation. Could be involved in the growth arrest and differentiation of the neuronal precursors (By similarity). Modulates transcription regulation mediated by ESR1. Involved in mitochondrial depolarization and neurite outgrowth. |
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