Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human BTG4
Specificity
This antibody detects endogenous levels of BTG4 at Human
Gene Name
BTG4 PC3B
Protein Name
Protein BTG4 (BTG family member 4) (Protein PC3b)
Other Name
Species
Human
Gene ID
54766
Uniprot
Q9NY30,
Species.1
Mouse
Gene ID.1
Uniprot.1
O70552
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Tissue Expression
Expressed in oocytes after germinal vesicle breakdown (PubMed:32502391). Expressed in testis and in olfactory epithelium.
Signaling_pathway
Genetic Information Processing >> Folding, sorting and degradation >> RNA degradation
Research Areas
Function
Adapter protein that bridges CNOT7, a catalytic subunit of the CCR4-NOT complex, to EIF4E (By similarity). Facilitates maternal mRNAs decay during the maturation of oocytes and in the fertilized egg, and is required for the maternal-zygotic transition (MZT), zygotic cleavage and initiation of embryonic development .