C/EBP γ Polyclonal Antibody
Ucallm_WP11332-50
Price range: $268.00 through $328.00
Product details
Background:
The C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein: a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. The C/EBP family consist of several related proteins, C/EBP alpha, C/EBP beta, C/EBP gamma, and C/EBP delta, that form homodimers and that form heterodimers with each other. CCAAT/enhancer binding protein gamma may cooperate with Fos to bind PRE-I enhancer elements. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2011],
Specifications
| Size | 50μL/100μL |
| Target | C/EBP γ |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 22kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CEBPG. AA range:31-80 |
| Specificity | C/EBP γ Polyclonal Antibody detects endogenous levels of C/EBP γ protein. |
| Gene Name | CEBPG |
| Protein Name | CCAAT/enhancer-binding protein gamma |
| Other Name | CEBPG; / CCAAT/enhancer-binding protein gamma; / C/EBP gamma |
| Species | Human |
| Gene ID | 1054 |
| Uniprot | P53567, |
| Species.1 | Mouse |
| Gene ID.1 | 12611 |
| Uniprot.1 | P53568, |
| Species.2 | Rat |
| Gene ID.2 | 25301 |
| Uniprot.2 | P26801 |
| Cellular Localization | Nucleus . |
| Tissue Expression | Placenta,T-cell,Trachea, |
| Signaling_pathway | |
| Research Areas | >>Tuberculosis |
| Function | Function:Transcription factor that binds to the enhancer element PRE-I (positive regulatory element-I) of the IL-4 gene. Might change the DNA-binding specificity of other transcription factors and recruit them to unusual DNA sites.,similarity:Belongs to the bZIP family. C/EBP subfamily.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer and can form stable heterodimers with C/EBP alpha and beta and with Fos protein., |
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