SKU: WP17774 Categories: ,

C-Jun (Hydroxylated-p244) rabbit pAb

Price range: $268.00 through $328.00

SKU: WP17774-100
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Product details

Background:

function:Transcription factor that recognizes and binds to the enhancer heptamer motif 5′-TGA[CG]TCA-3′., PTM:Phosphorylation enhances the transcriptional activity. Phosphorylated by PRKDC., similarity:Belongs to the bZIP family., similarity:Belongs to the bZIP family. Jun subfamily., similarity:Contains 1 bZIP domain., subunit:Heterodimer with either FOS or BATF3. Interacts with HIVEP3 (By similarity). Interacts with SMAD3/SMAD4 heterodimers. Interacts with MYBBP1A, SPIB and TCF20. Interacts with COPS5; indirectly leading to its phosphorylation. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA.,

Specifications

Targetc-JUN
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)39-42kD
Host SpeciesRabbit
IsotypeIgG
Conjugate
ModificationUnmodified
Recommended Dilution RatioWB 1:1000-2000;ELISA 1:5000-20000
CompositionLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Purification ProcessThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage Condition-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human C-Jun (Hydroxylated-p244)
Sequence
SpecificityThis antibody detects endogenous levels of Human, Mouse, Rat C-Jun (Hydroxylated-p244)
Gene NameJUN
Protein NameC-Jun (Hydroxylated-p244); Transcription factor AP-1;jun;c-jun;AP-1
AliasTranscription factor AP-1;Activator protein 1;AP1;Proto-oncogene c-Jun;V-jun avian sarcoma virus 17 oncogene homolog;p39;
Organism-1Human
Gene ID-13725
SwissProt-1P05412
Organism-2Mouse
Gene ID-216476
SwissProt-2P05627
Organism-3Rat
Gene ID-324516
SwissProt-3P17325
Organism-4
Gene ID-4
SwissProt-4
Cellular LocalizationNucleus.
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