C-Jun (Hydroxylated-p244) rabbit pAb
Product details
Background:
function:Transcription factor that recognizes and binds to the enhancer heptamer motif 5′-TGA[CG]TCA-3′., PTM:Phosphorylation enhances the transcriptional activity. Phosphorylated by PRKDC., similarity:Belongs to the bZIP family., similarity:Belongs to the bZIP family. Jun subfamily., similarity:Contains 1 bZIP domain., subunit:Heterodimer with either FOS or BATF3. Interacts with HIVEP3 (By similarity). Interacts with SMAD3/SMAD4 heterodimers. Interacts with MYBBP1A, SPIB and TCF20. Interacts with COPS5; indirectly leading to its phosphorylation. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA.,
Specifications
| Target | c-JUN |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 39-42kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate | |
| Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:1000-2000;ELISA 1:5000-20000 |
| Composition | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | |
| Purification Process | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Purity | |
| Storage Condition | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human C-Jun (Hydroxylated-p244) |
| Sequence | |
| Specificity | This antibody detects endogenous levels of Human, Mouse, Rat C-Jun (Hydroxylated-p244) |
| Gene Name | JUN |
| Protein Name | C-Jun (Hydroxylated-p244); Transcription factor AP-1;jun;c-jun;AP-1 |
| Alias | Transcription factor AP-1;Activator protein 1;AP1;Proto-oncogene c-Jun;V-jun avian sarcoma virus 17 oncogene homolog;p39; |
| Organism-1 | Human |
| Gene ID-1 | 3725 |
| SwissProt-1 | P05412 |
| Organism-2 | Mouse |
| Gene ID-2 | 16476 |
| SwissProt-2 | P05627 |
| Organism-3 | Rat |
| Gene ID-3 | 24516 |
| SwissProt-3 | P17325 |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Cellular Localization | Nucleus. |
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