SKU: WP8107 Categories: ,

C10orf58 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP8107-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetPRXL2A
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)25kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human C10orf58
SpecificityThis antibody detects endogenous levels of C10orf58 at Human, Mouse,Rat
Gene NameFAM213A C10orf58 PAMM PRO2290 PSEC0139 UNQ611/PRO1198
Protein NameRedox-regulatory protein FAM213A (Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes) (Protein PAMM)
Other Name
SpeciesHuman
Gene ID84293
UniprotQ9BRX8,
Species.1Mouse
Gene ID.170564
Uniprot.1Q9CYH2,
Species.2Rat
Gene ID.2361118
Uniprot.2Q6AXX6
Cellular LocalizationCytoplasm . Secreted . Secreted from mature adipocytes but not from preadipocytes. .
Tissue ExpressionExpressed in CSF1 and TNFSF11-stimulated CD14(+) peripheral blood mononuclear cells (PBMCs).
Signaling_pathway
Research Areas
FunctionInvolved in redox regulation of the cell . Acts as an antioxidant . Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation . May affect bone resorption and help to maintain bone mass . Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway .
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