SKU: WP7308 Categories: ,

C11orf30 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP7308-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetEMSY
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)145kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human C11orf30
SpecificityThis antibody detects endogenous levels of C11orf30 at Human, Mouse
Gene NameEMSY C11orf30 GL002
Protein NameProtein EMSY
Other Name
SpeciesHuman
Gene ID56946
UniprotQ7Z589,
Species.1Mouse
Gene ID.1233545
Uniprot.1Q8BMB0
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus . Localizes to DNA damage markers in irradiated cells, suggesting that it participates in DNA repair process.
Tissue Expression
Signaling_pathway
Research Areas
FunctionRegulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin . Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2 . Mediates ligand-dependent transcriptional activation by nuclear hormone receptors .
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