Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human C11orf30
Specificity
This antibody detects endogenous levels of C11orf30 at Human, Mouse
Gene Name
EMSY C11orf30 GL002
Protein Name
Protein EMSY
Other Name
Species
Human
Gene ID
56946
Uniprot
Q7Z589,
Species.1
Mouse
Gene ID.1
233545
Uniprot.1
Q8BMB0
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Nucleus . Localizes to DNA damage markers in irradiated cells, suggesting that it participates in DNA repair process.
Tissue Expression
Signaling_pathway
Research Areas
Function
Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin . Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2 . Mediates ligand-dependent transcriptional activation by nuclear hormone receptors .