Product details
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C15orf27 rabbit pAb
Ucallm_WP8170-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | TMEM266 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 58kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human C15orf27 |
| Specificity | This antibody detects endogenous levels of C15orf27 at Human, Mouse |
| Gene Name | C15orf27 |
| Protein Name | Transmembrane protein C15orf27 |
| Other Name | |
| Species | Human |
| Gene ID | 123591 |
| Uniprot | Q2M3C6, |
| Species.1 | Mouse |
| Gene ID.1 | 244886 |
| Uniprot.1 | Q8BZB3 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Multi-pass membrane protein . Cell projection, dendrite . Perikaryon . Present in the dendrites and soma of cerebellar granule neurons, but not in their axon. . |
| Tissue Expression | Mainly expressed in the cerebellum (PubMed:25165868). Also expressed in cerebral cortex, skeletal muscle and thyroid, but at much lower levels (PubMed:25165868). |
| Signaling_pathway | |
| Research Areas | |
| Function | Voltage-sensor protein present on the post-synaptic side of glutamatergic mossy fibers and granule cells in the cerebellum . Despite the presence of a voltage-sensor segment, does not form a functional ion channel and its precise role remains unclear . Undergoes both rapid and slow structural rearrangements in response to changes in voltage . Contains a zinc-binding site that can regulate the slow conformational transition . |
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