Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human C16orf63
Specificity
This antibody detects endogenous levels of C16orf63 at Human, Mouse
Gene Name
FOPNL C16orf63 FOR20 PHSECRG2
Protein Name
LisH domain-containing protein FOPNL (FGFR1OP N-terminal-like protein) (FOP-related protein of 20 kDa)
Other Name
Species
Human
Gene ID
123811
Uniprot
Q96NB1,
Species.1
Mouse
Gene ID.1
66086
Uniprot.1
Q9CZS3
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cell projection, cilium . Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasmic granule . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite . Localizes to the centrosome throughout cell cycle progression (PubMed:24018379). Localization to centrioles and pericentriolar satellites may be mediated by KIAA0753/OFIP (PubMed:26643951). .
Tissue Expression
Widely expressed. Detected in brain, heart, kidney, liver, lung, skeletal muscle, placenta and intestine.
Signaling_pathway
Research Areas
Function
Involved in the biogenesis of cilia . Required for the recruitment of PLK1 to centrosomes and S phase progression .