C1orf187 rabbit pAb
Ucallm_WP8537-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | DRAXIN |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 38kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human C1orf187 |
| Specificity | This antibody detects endogenous levels of C1orf187 at Human, Mouse |
| Gene Name | DRAXIN C1orf187 PSEC0258 UNQ3119/PRO10268 |
| Protein Name | Draxin (Dorsal inhibitory axon guidance protein) (Dorsal repulsive axon guidance protein) (Neucrin) |
| Other Name | |
| Species | Human |
| Gene ID | 374946 |
| Uniprot | Q8NBI3, |
| Species.1 | Mouse |
| Gene ID.1 | 70433 |
| Uniprot.1 | Q6PAL1 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. |
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