Product details
Background:
C1orf86 rabbit pAb
Ucallm_WP7972-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | FAAP20 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 20kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human C1orf86 |
| Specificity | This antibody detects endogenous levels of C1orf86 at Human, Mouse,Rat |
| Gene Name | FAAP20 C1orf86 FP7162 |
| Protein Name | Fanconi anemia-associated protein of 20 kDa |
| Other Name | |
| Species | Human |
| Gene ID | 199990 |
| Uniprot | Q6NZ36, |
| Species.1 | Mouse |
| Gene ID.1 | 67513 |
| Uniprot.1 | Q3UN58, |
| Species.2 | Rat |
| Gene ID.2 | 362678 |
| Uniprot.2 | D4AAA5 |
| Cellular Localization | Nucleus . Chromosome . Following DNA damage, recruited to DNA interstrand cross-links (ICLs) sites by binding to ubiquitin generated by RNF8. . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction with REV1. |
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