Product details
Background:
C7orf43 rabbit pAb
Ucallm_WP8437-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | TRAPPC14 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 64kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human C7orf43 |
| Specificity | This antibody detects endogenous levels of C7orf43 at Human, Mouse |
| Gene Name | C7orf43 |
| Protein Name | Uncharacterized protein C7orf43 |
| Other Name | |
| Species | Human |
| Gene ID | 55262 |
| Uniprot | Q8WVR3, |
| Species.1 | Mouse |
| Gene ID.1 | 231807 |
| Uniprot.1 | Q3UTZ3 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm, cytoskeleton, spindle . Vesicle . Midbody . Cytoplasm . During mitosis, precedes alpha-tubulin in gap formation of cell abscission at the midbody and is co-localized with PLK1 at the edges of microtubules extensions of daughter cells post cytokinesis abscission (PubMed:30715179). Colocalizes with RAB3IP on preciliary vesicles (PubMed:31467083). . |
| Tissue Expression | Broadly expressed. High levels in brain, cerebellum, testis and whole blood. |
| Signaling_pathway | |
| Research Areas | |
| Function | Specific subunit of the TRAPP (transport protein particle) II complex, a highly conserved vesicle tethering complex that functions in late Golgi trafficking as a membrane tether . TRAPP II complex has also GEF activity toward RAB1A (By similarity). TRAPPC14 is dispensable for TRAPPII complex integrity but mediates RAB3IP preciliary vesicle trafficking to the mother centriole during ciliogenesis . Modulates YAP1 activity as transcriptional regulator . |
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