C8orf41 rabbit pAb
Ucallm_WP8179-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | TTI2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 56kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human C8orf41 |
| Specificity | This antibody detects endogenous levels of C8orf41 at Human, Mouse,Rat |
| Gene Name | TTI2 C8orf41 |
| Protein Name | TELO2-interacting protein 2 |
| Other Name | |
| Species | Human |
| Gene ID | 80185 |
| Uniprot | Q6NXR4, |
| Species.1 | Mouse |
| Gene ID.1 | 234138 |
| Uniprot.1 | Q8BGV4, |
| Species.2 | Rat |
| Gene ID.2 | 290811 |
| Uniprot.2 | Q66H56 |
| Cellular Localization | |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. |
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