Price range: $268.00 through $328.00
Background:
This gene encodes a cell-surface protein that is similar to CD99. A similar protein in mouse functions as an adhesion molecule during leukocyte extravasation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010],
| Size | 50μL/100μL |
| Target | C99L2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 29kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human C99L2 AA range: 204-254 |
| Specificity | This antibody detects endogenous levels of C99L2 at Human/Mouse/Rat |
| Gene Name | CD99L2 MIC2L1 UNQ1964/PRO4486 |
| Protein Name | C99L2 |
| Other Name | |
| Species | Human |
| Gene ID | 83692 |
| Uniprot | Q8TCZ2, |
| Species.1 | Mouse |
| Gene ID.1 | 171486 |
| Uniprot.1 | Q8BIF0, |
| Species.2 | Rat |
| Gene ID.2 | 171485 |
| Uniprot.2 | Q8R1R5 |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein; Extracellular side . Cell junction . |
| Tissue Expression | Expressed in many tissues, with low expression in thymus. |
| Signaling_pathway | Organismal Systems >> Immune system >> Leukocyte transendothelial migration;Environmental Information Processing >> Signaling molecules and interaction >> Cell adhesion molecules |
| Research Areas | >>Cell adhesion molecules; / >>Leukocyte transendothelial migration |
| Function | Function:May function as a homophilic adhesion molecule. Functions in leukocyte-endothelial cell interactions during leukocyte extravasation, and in particular, at the diapedesis step. Does not seem to be involved in docking of leukocytes to the vessel wall or in lymphocyte diapedesis.,PTM:O-glycosylated.,similarity:Belongs to the CD99 family.,tissue specificity:Expressed in brain, heart, lung, liver, spleen, kidney, stomach, small intestine, skeletal muscle, ovary, thymus, testis and uterus. Lower expression seen in thymus. Expressed in E18 uterus and placenta., |
