Need Help? +(1)-866-986-9598
0 My Cart$0.00
Home/Reagents/Antibody/Primary antibody/Polyclonal Antibody/Rabbit pAb/CACB1 rabbit pAb
SKU: WP16541 Categories: ,

CACB1 rabbit pAb

Ucallm_WP16541-50

Price range: $268.00 through $328.00

SKU: WP16541-100
Enter the quantity you would like, or drag the panel to find the quantity and price that best for you
Bulk QuoteAuthorize OEM & ODM

Product details

Background:

The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetCACB1
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)66kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human CACB1 AA range: 79-129
SpecificityThis antibody detects endogenous levels of CACB1 at Human/Mouse/Rat
Gene NameCACNB1 CACNLB1
Protein NameCACB1
Other Name
SpeciesHuman
Gene ID782
UniprotQ02641,
Species.1Mouse
Gene ID.112295
Uniprot.1Q8R3Z5,
Species.2Rat
Gene ID.250688
Uniprot.2P54283
Cellular LocalizationCell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side . Cell membrane; Peripheral membrane protein .
Tissue ExpressionDetected in heart ventricle (at protein level) (PubMed:15615847). Isoform 1 and isoform 3 are expressed in brain, heart, spleen, central nervous system and neuroblastoma cells. Isoform 2 is expressed in skeletal muscle.
Signaling_pathwayOrganismal Systems >> Endocrine system >> Oxytocin signaling pathway;Organismal Systems >> Circulatory system >> Cardiac muscle contraction;Organismal Systems >> Circulatory system >> Adrenergic signaling in cardiomyocytes;Environmental Information Processing >> Signal transduction >> MAPK signaling pathway
Research Areas>>MAPK signaling pathway; / >>Cardiac muscle contraction; / >>Adrenergic signaling in cardiomyocytes; / >>Oxytocin signaling pathway; / >>Hypertrophic cardiomyopathy; / >>Arrhythmogenic right ventricular cardiomyopathy; / >>Dilated cardiomyopathy
FunctionFunction:The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.,similarity:Belongs to the calcium channel beta subunit family.,similarity:Contains 1 SH3 domain.,subunit:The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma. Interacts with JSRP1.,tissue specificity:Expressed in brain, heart and spleen (isoform 1 and 3) and in skeletal muscle (isoform 2).,
Please login to post questions

Related products
Sku: W2209
Categories: ,

U-Blot™ Phosphate Buffered Saline with Tween 20 (PBS-T), pH 7.4

0 Reviews
$199.00
Add to cartBulk Quote
Western blot analysis of lysates from K562 cells, using α smooth muscle actin Rabbit mAb. The HRP-conjugated Goat anti-Rabbit IgG antibody (WS0002) was used to detect the antibody.
Sku: WR4021
Categories: ,

U-Blot® α smooth muscle actin Rabbit mAb

0 Reviews
Price range: $268.00 through $328.00
Select options
Sku: WR4014
Categories: ,

U-Blot® HDAC2 Rabbit mAb

0 Reviews
Price range: $268.00 through $328.00
Select options
Sku: WR4003
Categories: ,

U-Blot® PMS2 Rabbit mAb

0 Reviews
Price range: $268.00 through $328.00
Select options
Sku: WR4004
Categories: ,

U-Blot® Cleaved PARP1 Rabbit mAb

0 Reviews
Price range: $268.00 through $328.00
Select options
J774A.1 whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with primary antibody(1:1000). The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody.
Sku: WR4005
Categories: ,

U-Blot® CD86 Rabbit mAb

0 Reviews
Price range: $268.00 through $328.00
Select options

Customer Reviews

  • Shop Categories
Menu
Need Help? +(1)-866-986-9598
Back to Top
Product has been added to your cart