SKU: WP11374 Categories: ,

Cadherin-26 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP11374-100
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Product details

Background:

Cadherins are a family of adhesion molecules that mediate Ca2+-dependent cell-cell adhesion in all solid tissues and modulate a wide variety of processes, including cell polarization and migration. Cadherin domains occur as repeats in the extracellular region and are thought to contribute to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. This gene encodes a cadherin domain-containing protein whose specific function has not yet been determined. Alternative splicing occurs at this locus and two transcript variants, encoding distinct proteins, have been identified. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetCadherin-26
ReactivityHuman, Mouse
ApplicationsWB, IF, ELISA
MW(Calculated)
MW(Observed)95kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human CDH26. AA range:11-60
SpecificityCadherin-26 Polyclonal Antibody detects endogenous levels of Cadherin-26 protein.
Gene NameCDH26
Protein NameCadherin-like protein 26
Other NameCDH26; / Cadherin-like protein 26; / Cadherin-like protein VR20
SpeciesHuman
Gene ID60437
UniprotQ8IXH8,
Species.1Mouse
Gene ID.1
Uniprot.1P59862
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCell membrane; Single-pass type I membrane protein .
Tissue ExpressionExpressed by epithelial cells of gastrointestinal tissue.
Signaling_pathway
Research Areas
FunctionFunction:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.,similarity:Contains 4 cadherin domains.,
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