CASPR3 Polyclonal Antibody
Product details
Background:
The protein encoded by this gene belongs to the NCP family of cell-recognition molecules. This family represents a distinct subgroup of the neurexins. NCP proteins mediate neuron-glial interactions in vertebrates and glial-glial contact in invertebrates. The protein encoded by this gene may play a role in cell recognition within the nervous system. Alternatively spliced transcript variants encoding different isoforms have been described but their biological nature has not been determined. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | CASPR3 |
| Reactivity | Human |
| Applications | IHC, IF, ELISA |
| MW(Calculated) | 141kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from the C-terminal region of human CASPR3..at AA range:1200-1260. |
| Specificity | CASPR3 Polyclonal Antibody detects endogenous levels of CASPR3 protein. |
| Gene Name | CNTNAP3 |
| Protein Name | Contactin-associated protein-like 3 |
| Other Name | CNTNAP3; / CASPR3; / KIAA1714; / Contactin-associated protein-like 3; / Cell recognition molecule Caspr3 |
| Species | Human |
| Gene ID | 79937 |
| Uniprot | Q9BZ76 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | [Isoform 1]: Cell membrane; Single-pass type I membrane protein .; [Isoform 2]: Secreted . |
| Tissue Expression | Brain,Human fetal brain,Prostate, |
| Signaling_pathway | |
| Research Areas | |
| Function | similarity:Belongs to the neurexin family.,similarity:Contains 1 F5/8 type C domain.,similarity:Contains 1 fibrinogen C-terminal domain.,similarity:Contains 2 EGF-like domains.,similarity:Contains 4 laminin G-like domains., |
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